Title

Gestational growth trajectories derived from a dynamic fetal-placental scaling law.

Contributing USMA Research Unit(s)

Mathematical Sciences

Publication Date

10-31-2019

Publication Title

Journal of the Royal Society, Interface

Document Type

Article

Abstract

Fetal trajectories characterizing growth rates in utero have relied primarily on goodness of fit rather than mechanistic properties exhibited in utero. Here, we use a validated fetal–placental allometric scaling law and a first principles differential equations model of placental volume growth to generate biologically meaningful fetal–placental growth curves. The growth curves form the foundation for understanding healthy versus at-risk fetal growth and for identifying the timing of key events in utero.

First Page

20190417

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